Hyperpituitarism - Definition, Causes, Symptoms And Treatment
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Hyperpituitarism, also called acromegaly and gigantism. Hyperpituitarism is the excessive production of growth hormone, which continues to be produced well. Hypersecretion of pituitary hormones secondary to macroadenomas can interfere with other pituitary hormone functions, resulting in target organ hormone deficiencies. Acromegaly occurs after epiphyseal closure, causing bone thickening and transverse growth and visceromegaly. This form of hyperpituitarism occurs equally among men and women, usually between the ages of 30 and 50. In most patients, the source of excessive growth hormone (GH) or human growth hormone secretion is a GH-producing adenoma of the anterior pituitary gland, usually macroadenoma (eosinophilic or mixed-cell). Since pituitary tumors (usually benign) are the most common cause of this condition, other areas controlled by the pituitary are often affected, such as Prolactin and thyroid hormones.
